NS-8
Product Specifications
UNSPSC Description
NS-8, a pyrrole derivative, activates the Ca2+-sensitive k+-channel. NS-8 can suppress the micturition reflex by decreasing afferent pelvic nerve activity. NS-8 can be used in the research of urinary frequency and incontinence[1].
Target Antigen
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/ns-8.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C2=C(F)C=CC=C2)NC(N)=C1C#N
Molecular Weight
215.23
References & Citations
[1]M Tanaka, et al. A novel pyrrole derivative, NS-8, suppresses the rat micturition reflex by inhibiting afferent pelvic nerve activity. BJU Int. 2003 Dec;92(9):1031-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147383/NS-8-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147383/
Clinical Information
Phase 1
CAS Number
186033-14-7
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