NS-8
NS-8, a pyrrole derivative, activates the Ca2+-sensitive k+-channel. NS-8 can suppress the micturition reflex by decreasing afferent pelvic nerve activity. NS-8 can be used in the research of urinary frequency and incontinence[1].
Product Specifications
CAS Number
186033-14-7
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/ns-8.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C2=C(F)C=CC=C2)NC(N)=C1C#N
Molecular Formula
C12H10FN3
Molecular Weight
215.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]M Tanaka, et al. A novel pyrrole derivative, NS-8, suppresses the rat micturition reflex by inhibiting afferent pelvic nerve activity. BJU Int. 2003 Dec;92 (9) :1031-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![MAGEB3 Mouse Monoclonal Antibody [Clone 5H8]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
MBS065435 Inquire
Fish Acetyl Coenzyme A Acetyltransferase 2 ELISA Kit
Sign In for Pricing
View Details ![Mouse Monoclonal p57 Kip2 Antibody (SPM308) [mFluor Violet 610 SE]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
NBP2-47765MFV610 0.1 mL
Mouse Monoclonal p57 Kip2 Antibody (SPM308) [mFluor Violet 610 SE]
Sign In for Pricing
View Details GTR15388355 1 Vial
Lentiviral human MARK2 sgRNA gene knockout kit - Lentiviral human MARK2 sgRNA gene knockout kit (plasmid)
Sign In for Pricing
View Details