NS-8
NS-8, a pyrrole derivative, activates the Ca2+-sensitive k+-channel. NS-8 can suppress the micturition reflex by decreasing afferent pelvic nerve activity. NS-8 can be used in the research of urinary frequency and incontinence[1].
Product Specifications
CAS Number
[186033-14-7]
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/ns-8.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C2=C(F)C=CC=C2)NC(N)=C1C#N
Molecular Formula
C12H10FN3
Molecular Weight
215.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147383/NS-8-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147383/
Scientific Category
Reference compound1
Clinical Information
Phase 1
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