MetRS-IN-1
MetRS-IN-1 (Compound 27) is an E. coli methionyl-tRNA synthetase (MetRS) inhibitor (IC50=237 nM) [1].
Product Specifications
CAS Number
24015-12-5
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/metrs-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC=C(/C=N/NC(CNC(C2=CC=CS2)=O)=O)C=C1
Molecular Formula
C15H13N3O4S
Molecular Weight
331.35
References & Citations
[1]Su Yeon Kim, et al. Pharmacophore-based virtual screening: the discovery of novel methionyl-tRNA synthetase inhibitors. Bioorg Med Chem Lett. 2006 Sep 15;16 (18) :4898-907.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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