HACC2-IN-1

HACC2-IN-1 is a potent acetyl-CoA carboxylase 2 (ACC2) inhibitor, with an IC50 value of 2.5 μM (hACC2) . hACC2-IN-1 could be used for obesity research[1].

Product Specifications

CAS Number

[192323-14-1]

UNSPSC

12352005

Target

Acetyl-CoA Carboxylase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/hacc2-in-1.html

Purity

99.86

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)(OC(NC[C@H]1CC[C@@H](CC1)CNS(=O)(C2=CC3=C(C=CC=C3)C=C2)=O)=O)C

Molecular Formula

C23H32N2O4S

Molecular Weight

432.58

References & Citations

[1]Bengtsson C, et al. Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats. Bioorg Med Chem. 2011 May 15;19 (10) :3039-53.