Bromodomain inhibitor-10
Bromodomain inhibitor-10 (compound 128) is a potent bromodomain inhibitor with Kds of 15.0, 2500 nM for BRD4-1 and BRD4-2, respectively. Bromodomain inhibitor-10 inhibits the production of IL12p40[1].
Product Specifications
CAS Number
[1870849-58-3]
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bromodomain-inhibitor-10.html
Solubility
10 mM in DMSO
Smiles
CC1=CC(NC2=C1C=C(NC(C3=C(N4CCOCC4)N=CC=C3)=O)C=C2)=O
Molecular Formula
C20H20N4O3
Molecular Weight
364.40
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]Jimmi GERNER SEITZBERG, et al. Compounds active towards bromodomains. WO2016016316A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD4
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
