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MAO-B-IN-14

MAO-B-IN-14 (Compound 9) is a potent and selective monoamine oxidase-B (MAO-B) inhibitor with an IC50 of 0.95 μM and a Ki of 0.55 μM against human MAO-B.

Product Specifications

CAS Number

1904610-48-5

UNSPSC

12352005

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mao-b-in-14.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(C=C1)SC)/C=C/C2=C3C(OCO3)=CC=C2

Molecular Formula

C17H14O3S

Molecular Weight

298.36

References & Citations

[1]Hammuda A, et al. Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors. Eur J Med Chem. 2016 May 23;114:162-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MAO-B

Frequently Asked Questions

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