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NMDA receptor potentiator-1

Product Specifications

UNSPSC Description

NMDA receptor potentiator-1 (Compound 1368) is a subunit selective NMDA receptor potentiator with IC50s of 4 μM and 5 μM against NR2C and NR2D expression, respectively[1].

Target Antigen

iGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nmda-receptor-potentiator-1.html

Solubility

10 mM in DMSO

Smiles

O=C(N1CCC2=CC(OC)=C(C=C2C1COC3=CC=C(C=C3)OC)OC)C4=CC=C(C=C4)Cl

Molecular Weight

467.94

References & Citations

[1]Stephen F. Traynelis, et al. Subunit selective NMDA receptor potentiators for the treatment of neurological conditions. Patent US8822462.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-147352/NMDA-receptor-potentiator-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-147352/

Clinical Information

No Development Reported

CAS Number

486427-18-3

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