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5-Methylcytidine 5′-triphosphate

5-Methylcytidine 5′-triphosphate (5-Methyl-CTP) is a modified nucleoside triphosphates. 5-Methylcytidine 5′-triphosphate can apply in replacing unmodified mRNA, resulting in the increase of translational properties and stability, as well as the reduction of innate immune responses in human and other mammalian cells[1].

Product Specifications

CAS Number

[327174-86-7]

Product Name Alternative

5-Methyl-CTP

UNSPSC

12352005

Hazard Statement

H371

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-methylcytidine-5-triphosphate.html

Solubility

10 mM in DMSO

Smiles

O[C@@H]1[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O[C@H]1N2C(N=C(N)C(C)=C2)=O

Molecular Formula

C10H18N3O14P3

Molecular Weight

497.18

Precautions

P260-P264-P270-P405-P501

References & Citations

[1]Shanmugasundaram M, et al. An Efficient Protection-Free One-Pot Chemical Synthesis of Modified Nucleoside-5'-Triphosphates. Nucleosides Nucleotides Nucleic Acids. 2016 Jul 2;35 (7) :356-62.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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