Epothilone E
Epothilone E is a related compound of epothilone, which inhibits microtubule protein function and blocks cell division, and has anti-tumor activity[1].
Product Specifications
CAS Number
[201049-37-8]
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/epothilone-e.html
Solubility
10 mM in DMSO
Smiles
OCC1=NC(/C=C([C@@H]2C[C@@]3([H])[C@](CCC[C@@H]([C@@H]([C@H](C(C(C)([C@H](CC(O2)=O)O)C)=O)C)O)C)([H])O3)\C)=CS1
Molecular Formula
C26H39NO7S
Molecular Weight
509.66
References & Citations
[1]K. C. Nicolaou, et al. Total synthesis of epothilone E and analogues with modified side chains through the Stille coupling reaction[J]. Angewandte Chemie International Edition, 1998, 37 (1‐2) : 84-87.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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