PI3K/mTOR Inhibitor-9
PI3K/mTOR Inhibitor-9 (Compound 1) is a potent mTOR and PI3K inhibitor with IC50 values of 38 nM, 6.6 μM, 6.6 μM and 0.8 μM against mTOR (phospho-S6 cellular assay), PI3Kα, PI3Kγ and PI3Kδ, respectively[1].
Product Specifications
CAS Number
[1392421-71-4]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
MTOR; PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pi3k-mtor-inhibitor-9.html
Solubility
10 mM in DMSO
Smiles
C[C@H]1N(CCOC1)C2=C3C(N=C(C4=C5C(NC=C5)=CC=C4)N3)=NC(N6[C@H](COCC6)C)=N2
Molecular Formula
C23H27N7O2
Molecular Weight
433.51
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MTOR; PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ
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