PI3K/mTOR Inhibitor-9
Product Specifications
UNSPSC Description
PI3K/mTOR Inhibitor-9 (Compound 1) is a potent mTOR and PI3K inhibitor with IC50 values of 38 nM, 6.6 μM, 6.6 μM and 0.8 μM against mTOR (phospho-S6 cellular assay), PI3Kα, PI3Kγ and PI3Kδ, respectively[1].
Target Antigen
mTOR; PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pi3k-mtor-inhibitor-9.html
Solubility
10 mM in DMSO
Smiles
C[C@H]1N(CCOC1)C2=C3C(N=C(C4=C5C(NC=C5)=CC=C4)N3)=NC(N6[C@H](COCC6)C)=N2
Molecular Weight
433.51
References & Citations
[1]Bonazzi S, et al. Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders. J Med Chem. 2020 Feb 13;63(3):1068-1083.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147285/PI3K-mTOR-Inhibitor-9-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147285/
Clinical Information
No Development Reported
CAS Number
1392421-71-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
