UC-1V150
Product Specifications
UNSPSC Description
UC-1V150 is a specific TLR7 (Toll-like receptor) agonist that stimulates cellular immune responses and has anti-tumor activity. UC-1V150 can be used to synthesize ISAC (Immune-Stimulating Antibody Conjugates) molecule[1][2].
Target Antigen
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/uc-1v150.html
Solubility
10 mM in DMSO
Smiles
O=CC1=CC=C(CN2C(NC3=C2N=C(OCCOC)N=C3N)=O)C=C1
Molecular Weight
343.34
References & Citations
[1]Christina C N Wu, et al. Immunotherapeutic activity of a conjugate of a Toll-like receptor 7 ligand. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3990-5.|[2]L N Dahal, et al. UC-1V150, a potent TLR7 agonist capable of activating macrophages and potentiating mAb-mediated target cell deletion. Scand J Immunol. 2018 Jun;87(6):e12666.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147215/UC-1V150-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147215/
Clinical Information
No Development Reported
CAS Number
927822-45-5
Curated Selection
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