Biotin-PEG-Alk (MW 5000)
Biotin-PEG-Alk (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG-Alk (MW 5000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
UNSPSC
12352211
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/biotin-peg-alk-mw-5000.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCC#C)CCCC[C@H]1SC[C@@]([C@@]1([H])N2)([H])NC2=O.[n].[MW5000]
Molecular Weight
5000 (Average)
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Frequently Asked Questions
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