3,6-Diamino-9 (10H) -acridone
3,6-Diamino-9 (10H) -acridone is a topoisomerase inhibitor[1].
Product Specifications
CAS Number
[42832-87-1]
UNSPSC
12352005
Hazard Statement
H302+H312+H332-H315-H319-H335
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/3-6-diamino-9-10h-acridone.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C=C(N)C=C2)NC3=CC(N)=CC=C13
Molecular Formula
C13H11N3O
Molecular Weight
225.25
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Nunhart P, et al. Fluorinated 3,6,9-trisubstituted acridine derivatives as DNA interacting agents and topoisomerase inhibitors with A549 antiproliferative activity. Bioorg Chem. 2020 Jan;94:103393.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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