1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine

1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine (DAPE) is a phospholipid phosphatidylethanolamine. Unlike other phospholipid phosphatidylethanolamines, 1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine has no significant effect on protein phosphatase PP2A activity and does not inhibit insulin-stimulated GLUT4 translocation[1].

Product Specifications

CAS Number

[5634-86-6]

Product Name Alternative

DAPE

UNSPSC

12352200

Hazard Statement

H225, H319

Target

Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/1-2-diarachidonoyl-sn-glycero-3-phosphoethanolamine.html

Concentration

1.27 mM * 500 μL in Ethanol

Purity

91.7

Solubility

10 mM in DMSO

Smiles

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[C@@H](COP(OCCN)(O)=O)COC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)=O

Molecular Formula

C45H74NO8P

Molecular Weight

788.04

Precautions

H225, H319

References & Citations

[1]Tsuchiya A, et al. Dipalmitoleoylphosphoethanolamine as a PP2A enhancer obstructs insulin signaling by promoting Ser/Thr dephosphorylation of Akt. Cell Physiol Biochem. 2014;34 (3) :617-27.