Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Rofapitide tetraxetan (acetate)

Rofapitide tetraxetan (FAP-2286) acetate is a potent and selective FAP-binding peptide with a mean IC50 value of 2.7 nM for binding to FAP. Rofapitide tetraxetan acetate can be labeled with radionuclides for diagnostic applications. Rofapitide tetraxetan acetate has antitumor activity[1].

Product Specifications

Product Name Alternative

FAP-2286 (acetate)

UNSPSC

12352005

Target

FAP

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fap-2286-acetate.html

Solubility

10 mM in DMSO

Smiles

O=C(N1[C@@](C(N[C@@](C(N[C@H](C(N[C@H](C2=O)CC3=CC=CC=C3)=O)CCC(N)=O)=O)([H])[C@H](O)C)=O)([H])CCC1)[C@@](CCC4)([H])N4C([C@H](CSCC5=CC(CSCCNC(CN(CCN(CC6)CC(O)=O)CCN(CCN6CC(O)=O)CC(O)=O)=O)=CC(CSC[C@H](N2)C(O)=O)=C5)NC(CCCCC)=O)=O.CC(O)=O

Molecular Formula

C69H103N13O20S3

Molecular Weight

1530.83

References & Citations

[1]Baum RP, et al. Feasibility, Biodistribution, and Preliminary Dosimetry in Peptide-Targeted Radionuclide Therapy of Diverse Adenocarcinomas Using 177Lu-FAP-2286: First-in-Humans Results. J Nucl Med. 2022 Mar;63 (3) :415-423.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Alpha-Sinensal
TRC-S487305-1MG 1 mg

Alpha-Sinensal

Sign In for Pricing
View Details
PDGF Receptor alpha (PDGFRA) Mouse Monoclonal Antibody [Clone ID: OTI1C10]
CF807645 100 µg

PDGF Receptor alpha (PDGFRA) Mouse Monoclonal Antibody [Clone ID: OTI1C10]

Sign In for Pricing
View Details
Frozen Tissue Sections, Myometrium
CS502943 5x 5 µm

Frozen Tissue Sections, Myometrium

Sign In for Pricing
View Details
HER4 (Ab-1284) Antibody
8B0947-AAT 50 µg

HER4 (Ab-1284) Antibody

Sign In for Pricing
View Details
BubR1 (BUB1B) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI10E7]
TA500606AM 100 µL

BubR1 (BUB1B) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI10E7]

Sign In for Pricing
View Details
1,3-Distearoyl-2-chloropropanediol
TRC-D493510-25MG 25 mg

1,3-Distearoyl-2-chloropropanediol

Sign In for Pricing
View Details