AMPK activator 7
AMPK activator 7 (compound I-3-24) is a an AMPK activator with the EC50 of 8.8 nM. AMPK activator 7 can be used for the research of diseases involving AMPK, particularly diseases such as type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia and/or hypertension[1].
Product Specifications
CAS Number
1623138-03-3
UNSPSC
12352005
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ampk-activator-7.html
Solubility
10 mM in DMSO
Smiles
FC1=C(C2=C(C=C(N3CCOCC3)C=C2F)F)N=C(C(N4)=C1)C=C4O[C@H]5[C@]6([H])[C@]([C@@H](CO6)O)([H])OC5
Molecular Formula
C23H22F3N3O5
Molecular Weight
477.43
References & Citations
[1]Indole and azaindole derivatives each having ampk-activating activity. WO2014133008A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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