MC-Val-D-Cit-PAB-PNP
MC-Val-D-Cit-PAB-PNP is a cleavable peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs) . MC-Val-D-Cit-PAB-PNP contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-nitrophenol (PNP) group that allows the peptide to be linked to antitumor compounds.
Product Specifications
CAS Number
[1350456-66-4]
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-val-d-cit-pab-pnp.html
Purity
98.08
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC(C=C1)=CC=C1COC(OC(C=C2)=CC=C2[N+]([O-])=O)=O)[C@@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN(C3=O)C(C=C3)=O)=O)=O
Molecular Formula
C35H43N7O11
Molecular Weight
737.76
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Protease Cleavable Linker
Available Sizes
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