NIOCH 14
NIOCH 14 is a antiviral agent and a pro-agent. NIOCH 14 has antiviral activity against orthopoxviruses. NIOCH 14 can significantly lower proportions of infected mice, and virus production levels in the lungs. NIOCH 14 can be used for researching anti-smallpox[1][2]. NIOCH 14 shows anti-orthopoxvirus activity.
Product Specifications
CAS Number
1268015-38-8
UNSPSC
12352005
Target
Orthopoxvirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nioch-14.html
Solubility
10 mM in DMSO
Smiles
O=C(C1C2C=CC(C3CC23)C1C(NNC(C4=CC=C(C(F)(F)F)C=C4)=O)=O)O
Molecular Formula
C19H17F3N2O4
Molecular Weight
394.34
References & Citations
[1]Sokolova AS, et al. (+) -Camphor and (-) -borneol derivatives as potential anti-orthopoxvirus agents. Arch Pharm (Weinheim) . 2021;354 (6) :e2100038.|[2]Mazurkov OY, et al. New effective chemically synthesized anti-smallpox compound NIOCH-14. J Gen Virol. 2016;97 (5) :1229-1239. |[3]Anastasiya S Sokolova, et al. (+) -Camphor and (-) -borneol derivatives as potential anti-orthopoxvirus agents. Arch Pharm (Weinheim) . 2021 Jun;354 (6) :e2100038.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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