Ecopipam
Ecopipam (SCH 39166) is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively) . Ecopipam can be used for the research of schizophrenia and obesity[1][3].
Product Specifications
CAS Number
112108-01-7
Product Name Alternative
SCH 39166
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ecopipam.html
Purity
99.77
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
OC1=C(Cl)C=C2C([C@]3([H])[C@@](CCC4=C3C=CC=C4)([H])N(C)CC2)=C1
Molecular Formula
C19H20ClNO
Molecular Weight
313.82
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
D1 Receptor; D2 Receptor; D4 Receptor; D5 Receptor; MUC4; α adrenergic receptor
Available Sizes
Frequently Asked Questions
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