ATX inhibitor 16
Product Specifications
UNSPSC Description
ATX inhibitor 16 is a potent ATX inhibitor with an IC50 of 0.0021 μM. ATX inhibitor 16 shows excellent anti-proliferative activities in breast cancer cells[1].
Target Antigen
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atx-inhibitor-16.html
Solubility
10 mM in DMSO
Smiles
OC1CCN(CC2=CSC(C3=CC4=C(N(CC)C=C4/C(C(F)(F)F)=N/NC5=NC6=CC=CC=C6S5)C=C3)=N2)CC1
Molecular Weight
584.68
References & Citations
[1]Lei H,et al. Structure guided design of potent indole-based ATX inhibitors bearing hydrazone moiety with tumor suppression effects. Eur J Med Chem. 2020 Sep 1;201:112456.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146889/ATX-inhibitor-16-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146889/
Clinical Information
No Development Reported
CAS Number
2484811-36-9
Curated Selection
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