As-358 (hydrochloride)
As-358 (hydrochloride) has inhibitory effects against Ebola virus and Marburg virus with IC50s of 9.1 μM and 18.1 μM, as well as exhibits good in vivo safety[1].
Product Specifications
CAS Number
2374723-26-7
UNSPSC
12352005
Target
Filovirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/as-358-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C(O[C@@H]1C[C@@H]2CC[C@]1(C2(C)C)C)CC[NH+]3CCCCC3.[Cl-]
Molecular Formula
C18H32ClNO2
Molecular Weight
329.91
References & Citations
[1]Sokolova AS, Yarovaya OI, Zybkina AV, et al. Monoterpenoid-based inhibitors of filoviruses targeting the glycoprotein-mediated entry process. Eur J Med Chem. 2020;207:112726.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EBOV; MARV
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