Tubulin polymerization-IN-10
Product Specifications
UNSPSC Description
Tubulin polymerization-IN-10 is a potent tubulin polymerization inhibitor with an IC50 of 4.25±0.75 μM. Tubulin polymerization-IN-10 has anti-tumor effects[1].
Target Antigen
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-polymerization-in-10.html
Solubility
10 mM in DMSO
Smiles
NC1=CC(/C=C/S(=O)(C2=CC(OC)=C(OC)C(OC)=C2)=O)=CC=C1OC
Molecular Weight
379.43
References & Citations
[1]Huajian Zhu, et al. Design, synthesis and biological evaluation of vinyl selenone derivatives as novel microtubule polymerization inhibitors. Eur J Med Chem . 2020 Dec 1;207:112716.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146863/Tubulin-polymerization-IN-10-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146863/
Clinical Information
No Development Reported
CAS Number
2238784-19-3
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