EBOV/MARV-IN-3
EBOV/MARV-IN-3 (compound 32) is a potent EBOV and MARV inhibitor with IC50 values of 0.5, 1.2 µM, respectively. EBOV/MARV-IN-3 binds to the hydrophobic pocket close to EBOV Y517. EBOV/MARV-IN-3 shows antiviral activity[1].
Product Specifications
CAS Number
2687245-05-0
UNSPSC
12352005
Target
Filovirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ebov-marv-in-3.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C(OC2=CC(OCC(CN3CCC(CC3)C(N)=O)O)=CC=C21)=O)CC4=CC=C(C=C4)OC(F)(F)F
Molecular Formula
C27H29F3N2O6
Molecular Weight
534.52
References & Citations
[1]Gao Y, et al. Development of coumarine derivatives as potent anti-filovirus entry inhibitors targeting viral glycoprotein. Eur J Med Chem. 2020 Oct 15;204:112595.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EBOV; MARV
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