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Galectin-3 antagonist 2

Galectin-3 is a β Galactoside specific carbohydrate recognition protein (lectin) has the ability to promote the migration of B cell precursor acute lymphoblastic leukemia (BCP-ALL) cells and withstand drug research.

Product Specifications

CAS Number

[2921603-02-1]

UNSPSC

12352005

Target

Galectin

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/galectin-3-antagonist-2.html

Solubility

10 mM in DMSO

Smiles

OC[C@H]1O[C@@H](OC)[C@@H](OC(C2=C([N+]([O-])=O)C=CC=C2)=O)[C@@H](OC(C3=CC=C(C)C=C3)=O)[C@H]1O

Molecular Formula

C22H23NO10

Molecular Weight

461.42

References & Citations

[1]Bum-Erdene K, et al. Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia. J Med Chem. 2022 Apr 28;65 (8) :5975-5989.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Galectin-3

Curated Selection

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