HIV-1 protease-IN-3
HIV-1 protease-IN-3 (compound 14) is a potent inhibitor of HIV-1 protease (IC50=71 nM; EC50=0.86 μM) [1].
Product Specifications
UNSPSC
12352005
Target
HIV; HIV Protease
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-protease-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@@](C2=CC=C(S(C)(=O)=O)C=C2O[C@@H](C)CO)(CCC(C)C)[C@@H](O)CN1CC3=CC=C(OC)C=C3
Molecular Formula
C27H37NO7S
Molecular Weight
519.65
References & Citations
[1]Kojima E, et al. Pocket-to-Lead: Structure-Based De Novo Design of Novel Non-peptidic HIV-1 Protease Inhibitors Using the Ligand Binding Pocket as a Template. J Med Chem. 2022 Apr 28;65 (8) :6157-6170.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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