NLRP3-IN-9
NLRP3-IN-9 is a potent NLRP3 inhibitor. NLRP3-IN-9 inhibits IL-1β release. NLRP3-IN-9 reduces inflammation and mechanical hyperalgesia. NLRP3-IN-9 has the potential for the research of gout[1].
Product Specifications
CAS Number
2768759-64-2
UNSPSC
12352005
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nlrp3-in-9.html
Solubility
10 mM in DMSO
Smiles
O=C(N([Na])S(C1=CC(C(C)(O)C)=CO1)(=O)=O)NC2=CC(C)=CC(C)=C2
Molecular Formula
C16H19N2NaO5S
Molecular Weight
374.39
References & Citations
[1]Narros-Fernández P, et al. Synthesis and Pharmacological Evaluation of New N-Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout. J Med Chem. 2022 Apr 28;65 (8) :6250-6260.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NLRP3
Available Sizes
Frequently Asked Questions
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