SDR-04
Product Specifications
UNSPSC Description
SDR-04 is a BET inhibitor and exhibits strong BRD4-BD1 affinity and inhibition activity. SDR-04 potently suppresses MV4;11 cancer cell line proliferation[1].
Target Antigen
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sdr-04.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(C2=C(N3C=CN=CC3=N2)NC4=CC=CC=C4)=CC=C1O
Molecular Weight
332.36
References & Citations
[1]Ru Dong, et al. Design, synthesis and anticancer evaluation of 3-methyl-1H-indazole derivatives as novel selective bromodomain-containing protein 4 inhibitors. Bioorg Med Chem. 2021 Dec 29;55:116592.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146741/SDR-04-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146741/
Clinical Information
No Development Reported
CAS Number
879593-54-1
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