BRD4 Inhibitor-19
BRD4 Inhibitor-19 is a BET inhibitor with an IC50 of 55 nM for BRD4-BD1. BRD4 Inhibitor-19 can be used for multiple myeloma research[1].
Product Specifications
CAS Number
2757865-63-5
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd4-inhibitor-19.html
Solubility
10 mM in DMSO
Smiles
CC1=NOC(C)=C1C2=CC=C3C(C(N(C(N3C)=O)CC4=NN=C(O4)C5=CC=CC=C5)C6=CC=CC=C6)=C2
Molecular Formula
C29H25N5O3
Molecular Weight
491.54
References & Citations
[1]Lincheng Fang, et al. Discovery of 3,5-dimethylisoxazole derivatives as novel, potent inhibitors for bromodomain and extraterminal domain (BET) family. Bioorg Med Chem. 2021 Jun 1;39:116133.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BD1
Frequently Asked Questions
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