GSD-11
Product Specifications
UNSPSC Description
GSD-11 is a potent and selective anti-austerity agent. GSD-11 inhibits the cell migration and colony formation of PANC-1 cells. GSD-11 inhibits the Akt/mTOR signaling pathway. GSD-11 has the potential for the research of pancreatic cancer[1].
Target Antigen
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gsd-11.html
Solubility
10 mM in DMSO
Smiles
[H][C@@]12CC[C@]3([C@@]4(CC(C([C@]4(CC[C@@]3([C@]1(CCC(C2)=O)C)[H])C)=C)=O)[H])[H]
Molecular Weight
300.44
References & Citations
[1]Kohyama A, et al. Structure-activity relationship and mechanistic study on guggulsterone derivatives; Discovery of new anti-pancreatic cancer candidate. Bioorg Med Chem. 2022; 54:116563.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146738/GSD-11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146738/
Clinical Information
No Development Reported
Curated Selection
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