GSD-11

GSD-11 is a potent and selective anti-austerity agent. GSD-11 inhibits the cell migration and colony formation of PANC-1 cells. GSD-11 inhibits the Akt/mTOR signaling pathway. GSD-11 has the potential for the research of pancreatic cancer[1].

Product Specifications

UNSPSC

12352211

Target

Akt

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gsd-11.html

Solubility

10 mM in DMSO

Smiles

[H][C@@]12CC[C@]3([C@@]4(CC(C([C@]4(CC[C@@]3([C@]1(CCC(C2)=O)C)[H])C)=C)=O)[H])[H]

Molecular Formula

C20H28O2

Molecular Weight

300.44

References & Citations

[1]Kohyama A, et al. Structure-activity relationship and mechanistic study on guggulsterone derivatives; Discovery of new anti-pancreatic cancer candidate. Bioorg Med Chem. 2022; 54:116563.