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PqsR-IN-2

PqsR-IN-2 (Compound 19) is a potent PqsR (Pseudomonas aeruginosa quorum sensing transcriptional regulator) inhibitor. PqsR-IN-1 attenuates pyocyanin production and has very low cytotoxicity[1].

Product Specifications

CAS Number

[2982271-63-4]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/pqsr-in-2.html

Solubility

10 mM in DMSO

Smiles

CCCCCCC1=NC(CN2C=NC3=CC=C(C=C3C2=O)Cl)=CS1

Molecular Formula

C18H20ClN3OS

Molecular Weight

361.89

References & Citations

[1]Scott Grossman, et al. Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR. Eur J Med Chem. 2020 Dec 15;208:112778.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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