PqsR-IN-2
Product Specifications
UNSPSC Description
PqsR-IN-2 (Compound 19) is a potent PqsR (Pseudomonas aeruginosa quorum sensing transcriptional regulator) inhibitor. PqsR-IN-1 attenuates pyocyanin production and has very low cytotoxicity[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pqsr-in-2.html
Solubility
10 mM in DMSO
Smiles
CCCCCCC1=NC(CN2C=NC3=CC=C(C=C3C2=O)Cl)=CS1
Molecular Weight
361.89
References & Citations
[1]Scott Grossman, et al. Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR. Eur J Med Chem. 2020 Dec 15;208:112778.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146706/PqsR-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146706/
Clinical Information
No Development Reported
CAS Number
2982271-63-4
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