PqsR-IN-2
PqsR-IN-2 (Compound 19) is a potent PqsR (Pseudomonas aeruginosa quorum sensing transcriptional regulator) inhibitor. PqsR-IN-1 attenuates pyocyanin production and has very low cytotoxicity[1].
Product Specifications
CAS Number
[2982271-63-4]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pqsr-in-2.html
Solubility
10 mM in DMSO
Smiles
CCCCCCC1=NC(CN2C=NC3=CC=C(C=C3C2=O)Cl)=CS1
Molecular Formula
C18H20ClN3OS
Molecular Weight
361.89
References & Citations
[1]Scott Grossman, et al. Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR. Eur J Med Chem. 2020 Dec 15;208:112778.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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