MtTMPK-IN-6

MtTMPK-IN-6 (compound 1) is a potent M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC50 value of 29 μM. MtTMPK-IN-6 can be used for researching tuberculosis[1].

Product Specifications

CAS Number

[2225885-99-2]

UNSPSC

12352005

Target

Bacterial; Thymidylate Synthase

Type

Reference compound

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mttmpk-in-6.html

Solubility

10 mM in DMSO

Smiles

CC1=CN(C(NC1=O)=O)C2CCN(CC2)CC3=CC=C(C=C3)OC4=CC=CC=C4

Molecular Formula

C23H25N3O3

Molecular Weight

391.46

References & Citations

[1]Jian Y, et al. Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents. Eur J Med Chem. 2020;206:112659.