IQTub4P
IQTub4P is a potent microtubule (MT) inhibitor. IQTub4P has the cytotoxicity in in HeLa cells, with EC50 of 170 nM. IQTub4P inhibits microtubule structure and function. IQTub4P is well-tolerated in vivo[1].
Product Specifications
CAS Number
2376321-67-2
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/iqtub4p.html
Solubility
10 mM in DMSO
Smiles
O=P(O[Na])(O[Na])OC1=CC2=C(C(C3=CC(OC)=C(C(OC)=C3)OC)=NC=C2)C=C1OC
Molecular Formula
C19H18NNa2O8P
Molecular Weight
465.30
References & Citations
[1]Kraus Y, Glas C, Melzer B, et al. Isoquinoline-based biaryls as a robust scaffold for microtubule inhibitors. Eur J Med Chem. 2020;186:111865.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC402203 20 µg
Pallidin (BLOC1S6) (NM_012388) Human Over-expression Lysate
Sign In for Pricing
View Details 
TRC-C955900-25MG 25 mg
(3S,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester
Sign In for Pricing
View Details 
