HDAC-IN-36
HDAC-IN-36 (compound 23 g) is an orally active and potent HDAC (histone deacetylase) inhibitor, with an IC50 of 11.68 nM (HDAC6) . HDAC-IN-36 promotes apoptosis, autophagy and suppresses migration. HDAC-IN-36 shows anti-tumor and anti-metastatic activity, and can be used for breast cancer research[1].
Product Specifications
CAS Number
2482992-54-9
UNSPSC
12352005
Target
Apoptosis; Autophagy; HDAC
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac-in-36.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(OC)=C2C(N=C(N=C2N3CCN(CC3)C)C4=CC(C)=C(C(C)=C4)OCCCCCC(NO)=O)=C1
Molecular Formula
C29H39N5O5
Molecular Weight
537.65
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC10; HDAC11; HDAC2; HDAC3; HDAC4; HDAC5; HDAC6; HDAC7; HDAC8; HDAC9
Frequently Asked Questions
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