IDO1/TDO-IN-2
Product Specifications
UNSPSC Description
IDO1/TDO-IN-2 (Compound 1) is a potent inhibitor of IDO1/TDO with IC50s of 0.1 and 0.07 μM. IDO1/TDO-IN-2 has the potential for the research of cancer diseases[1].
Target Antigen
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ido1-tdo-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=CC=CC=C2C(C3=C1N=NN3C4=CC=CC=C4)=O
Molecular Weight
275.26
References & Citations
[1]Pan S, et al. Discovery and structure-activity relationship studies of 1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives as potent dual inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1) and trytophan 2,3-dioxygenase (TDO). Eur J Med Chem. 2020 Dec 1;207:112703.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146673/IDO1-TDO-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146673/
Clinical Information
No Development Reported
CAS Number
5466-47-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
