IDO1/TDO-IN-2
IDO1/TDO-IN-2 (Compound 1) is a potent inhibitor of IDO1/TDO with IC50s of 0.1 and 0.07 μM. IDO1/TDO-IN-2 has the potential for the research of cancer diseases[1].
Product Specifications
CAS Number
[5466-47-7]
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ido1-tdo-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=CC=CC=C2C(C3=C1N=NN3C4=CC=CC=C4)=O
Molecular Formula
C16H9N3O2
Molecular Weight
275.26
References & Citations
[1]Pan S, et al. Discovery and structure-activity relationship studies of 1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives as potent dual inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1) and trytophan 2,3-dioxygenase (TDO) . Eur J Med Chem. 2020 Dec 1;207:112703.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
124968 100 µg
CHRAC1 (Chromatin Accessibility Complex Protein 1, CHRAC-1, Chromatin Accessibility Complex 15kD Protein, CHRAC-15, HuCHRAC15, DNA Polymerase Epsilon Subunit p15, CHRAC15)
Ask
View Details