STAT3-IN-9
Product Specifications
UNSPSC Description
STAT3-IN-9 is a potent STAT3 inhibitor. STAT3-IN-9 inhibits the activation of STAT3 (Tyr705) without influencing the phosphorylation of STAT1 (Tyr701). STAT3-IN-9 induces apoptosis and cell cycle arrest at the G2/M phase[1].
Target Antigen
Apoptosis; STAT
Type
Reference compound
Related Pathways
Apoptosis;JAK/STAT Signaling;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stat3-in-9.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(NC2=CC(C3=CC=NN3C)=CC4=C2OC(C(C)=O)=C4)=CC(OC)=C1
Molecular Weight
391.42
References & Citations
[1]Wang F, et al. Identification of novel STAT3 inhibitors bearing 2-acetyl-7-phenylamino benzofuran scaffold for antitumour study. Bioorg Med Chem. 2020; 28(24):115822.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146666/STAT3-IN-9-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146666/
Clinical Information
No Development Reported
CAS Number
2987726-27-0
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