AChE/BChE-IN-5
AChE/BChE-IN-5 (BMC-16) is a dual AChE and BChE inhibitor with IC50 values of 266 nM and 10.6 nM against human AChE (hAChE) and human BChE (hBChE), respectively. AChE/BChE-IN-5 can cross the BBB[1].
Product Specifications
CAS Number
[2410992-68-4]
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-bche-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C(OC1=CC=C(C(O)CNC2CCCCC2)C=C1)N(C)C
Molecular Formula
C17H26N2O3
Molecular Weight
306.40
References & Citations
[1]Wu J, et al. Design, synthesis and biological evaluation of novel carbamates as potential inhibitors of acetylcholinesterase and butyrylcholinesterase. Bioorg Med Chem. 2020 Mar 1;28 (5) :115324.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE
Curated Selection
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