AChE/BChE-IN-3 (hydrochloride)

AChE/BChE-IN-3 (BMC-1) hydrochloride is a dual AChE and BChE inhibitor with IC50 values of 6.08 μM and 0.383 μM against electric eel AChE (elAChE) and equine serum BChE (eqBChE), respectively[1].

Product Specifications

CAS Number

[2410992-69-5]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ache-bche-in-3-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

O=C(OC1=CC=CC(C(O)CNC(C)(C)C)=C1)N(C)C.[H]Cl

Molecular Formula

C15H25ClN2O3

Molecular Weight

316.82

References & Citations

[1]Wu J, et al. Design, synthesis and biological evaluation of novel carbamates as potential inhibitors of acetylcholinesterase and butyrylcholinesterase. Bioorg Med Chem. 2020 Mar 1;28 (5) :115324.