AChE/BChE-IN-3
AChE/BChE-IN-3 (BMC-1) is a dual AChE and BChE inhibitor with IC50 values of 6.08 μM and 0.383 μM against electric eel AChE (elAChE) and equine serum BChE (eqBChE), respectively[1].
Product Specifications
CAS Number
2410992-65-1
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-bche-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(OC1=CC=CC(C(O)CNC(C)(C)C)=C1)N(C)C
Molecular Formula
C15H24N2O3
Molecular Weight
280.36
References & Citations
[1]Wu J, et al. Design, synthesis and biological evaluation of novel carbamates as potential inhibitors of acetylcholinesterase and butyrylcholinesterase. Bioorg Med Chem. 2020 Mar 1;28 (5) :115324.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE
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