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Aldose reductase-IN-4

Aldose reductase-IN-4 (compund IIc) is an aldose reductase inhibitor with IC50s of 11.70 μM and 0.98 μM for aldehyde reductase 1 (ALR1) and ALR2, respectively[1].

Product Specifications

CAS Number

2446136-17-8

UNSPSC

12352005

Target

Aldose Reductase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aldose-reductase-in-4.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(C(F)=C1)O)(N2C=CC3=C2C=CC=C3)=O

Molecular Formula

C14H10FNO3S

Molecular Weight

291.30

References & Citations

[1]Konstantinos Koutsopoulos, et al. Design synthesis and evaluation of novel aldose reductase inhibitors: The case of indolyl-sulfonyl-phenols. Bioorg Med Chem. 2020 Aug 1;28 (15) :115575.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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