Aldose reductase-IN-4
Aldose reductase-IN-4 (compund IIc) is an aldose reductase inhibitor with IC50s of 11.70 μM and 0.98 μM for aldehyde reductase 1 (ALR1) and ALR2, respectively[1].
Product Specifications
CAS Number
2446136-17-8
UNSPSC
12352005
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aldose-reductase-in-4.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(C(F)=C1)O)(N2C=CC3=C2C=CC=C3)=O
Molecular Formula
C14H10FNO3S
Molecular Weight
291.30
References & Citations
[1]Konstantinos Koutsopoulos, et al. Design synthesis and evaluation of novel aldose reductase inhibitors: The case of indolyl-sulfonyl-phenols. Bioorg Med Chem. 2020 Aug 1;28 (15) :115575.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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