Glutaminase-IN-4
Glutaminase-IN-4 (compound 2a) is a glutaminase (GLS) inhibitor with an IC50 of 2.3 μM[1].
Product Specifications
CAS Number
1439390-05-2
UNSPSC
12352005
Target
Glutaminase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/glutaminase-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=NN=C(S1)CCCC2=NN=C(S2)NC(CC3=CC=CC=C3)=O)CC4=CC=CC=C4
Molecular Formula
C23H22N6O2S2
Molecular Weight
478.59
References & Citations
[1]Bridget Duvall, et al. Allosteric kidney-type glutaminase (GLS) inhibitors with a mercaptoethyl linker. Bioorg Med Chem. 2020 Oct 15;28 (20) :115698.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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