Glyoxalase I inhibitor 4

Glyoxalase I inhibitor 4 (compound 14) is a potent glyoxalase I inhibitor with an Ki of 10 nM[1].

Glyoxalase (GLO)

Reference compound

Metabolic Enzyme/Protease

Cancer-programmed cell death

Cancer

https://www.medchemexpress.com/glyoxalase-i-inhibitor-4.html

10 mM in DMSO

N[C@H](C(O)=O)CCC(N[C@H](C(NCC(O)=O)=O)CSC(N(C1=CC=C(C=C1)I)O)=O)=O

568.34

[1]Jin T,et al. Recent advances in the discovery and development of glyoxalase I inhibitors. Bioorg Med Chem. 2020 Feb 15;28(4):115243.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-146656/Glyoxalase-I-inhibitor-4-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-146656/

No Development Reported

250155-72-7