Glyoxalase I inhibitor 1
Product Specifications
UNSPSC Description
Glyoxalase I inhibitor 1 (compound 23) is a potent glyoxalase I (GLO1) inhibitor with an IC50 of 26 nM[1]. Glyoxalase I inhibitor 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
Glyoxalase (GLO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/glyoxalase-i-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
C#CCCCC(NC1=CC=C(C=C1)C(C2=CC=C(C=C2)NC3=NC=C(C(NC4=C(C=CC=C4)NS(C)(=O)=O)=N3)F)=O)=O
Molecular Weight
586.64
References & Citations
[1]Jin T, Zhao L, et al. Recent advances in the discovery and development of glyoxalase I inhibitors. Bioorg Med Chem. 2020 Feb 15;28(4):115243.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146653/Glyoxalase-I-inhibitor-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146653/
Clinical Information
No Development Reported
CAS Number
1622952-07-1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
