LpxC-IN-9
LpxC-IN-9 (compound 19) is a potent LpxC inhibitor. LpxC-IN-9 has antibacterial and hypotensive effects[1]. LpxC-IN-9 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
2756125-46-7
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/lpxc-in-9.html
Solubility
10 mM in DMSO
Smiles
CS[C@H](N(C=O)O)CN1N=NC2=C1C=CC(C#CC3=CC=C(C=C3)CN4CCOCC4)=C2
Molecular Formula
C23H25N5O3S
Molecular Weight
451.54
References & Citations
[1]Takeru Furuya, et al. N-Hydroxyformamide LpxC inhibitors, their in vivo efficacy in a mouse Escherichia coli infection model, and their safety in a rat hemodynamic assay. Bioorg Med Chem. 2020 Dec 15;28 (24) :115826.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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