Cyclophilin inhibitor 3
Cyclophilin inhibitor 3 (compound 7c) is a potent cyclophilin A (CypA) inhibitor with an potent anti-HCV activity (EC50 of 4.2 μM) [1].
Product Specifications
CAS Number
1676100-30-3
UNSPSC
12352005
Target
Cyclophilin; HCV
Type
Reference compound
Related Pathways
Anti-infection; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cyclophilin-inhibitor-3.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1OC)CCN(C(C2=CC=C(C=C2)[N+]([O-])=O)C(NC3CCCCC3)=O)C(CC4=CNC5=CC=CC=C45)=O
Molecular Formula
C34H38N4O6
Molecular Weight
598.69
References & Citations
[1]Xiaoli Li, et al. SAR study of bisamides as cyclophilin a inhibitors for the development of host-targeting therapy for hepatitis C virus infection. Bioorg Med Chem. 2020 Oct 1;28 (19) :115679.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cyclophilin A
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