SEH inhibitor-3
SEH inhibitor-3 (compound 35) is a potent and orally active soluble epoxide hydrolase (sEH) inhibitor with a Ki of 0.75 nM for human sEH[1].
Product Specifications
CAS Number
1809885-35-5
UNSPSC
12352005
Target
Epoxide Hydrolase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/seh-inhibitor-3.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1CCN(CC1)C(C2CCOCC2)=O)NC3=CC=C(C(F)=C3)OC(F)(F)F
Molecular Formula
C19H23F4N3O4
Molecular Weight
433.40
References & Citations
[1]Kin Sing Stephen Lee, et al. Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties and potencies for treating diabetic neuropathic pain. Bioorg Med Chem. 2020 Nov 15;28 (22) :115735.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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