VIM-2-IN-1
VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activities. VIM-2-IN-1 has moderate IC50 values of 23 µM, 48 µM and 231 µM for Verona integron-encoded metallo-β-lactamase (VIM-2), German imipenemase-1 (GIM-1) and New Delhi metallo-β-lactamase (NDM-1), respectively[1].
Product Specifications
CAS Number
[2452118-54-4]
UNSPSC
12352005
Target
Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/vim-2-in-1.html
Solubility
10 mM in DMSO
Smiles
CC(OCC1=C(N=NN1)CNS(=O)(C2=CC=C(C=C2)I)=O)=O
Molecular Formula
C12H13IN4O4S
Molecular Weight
436.23
References & Citations
[1] Zeeshan Muhammad, et al. Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases. Bioorg Med Chem. 2020 Aug 1;28 (15) :115598.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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