GLS1 Inhibitor-3
GLS1 Inhibitor-3 (compound C147) is a potent GLS1 inhibitor with an IC50 of 27.98 nM. GLS1 Inhibitor-3 shows antiproliferative activity[1].
Product Specifications
CAS Number
[2435781-94-3]
UNSPSC
12352005
Target
Glutaminase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gls1-inhibitor-3.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(C=C1)CN2C=C(N=N2)CCC(NC3=CC=C(N=N3)CCCCC4=NN=C(S4)NC(CC5=NC=CC=C5)=O)=O
Molecular Formula
C30H32N10O2S
Molecular Weight
596.71
References & Citations
[1]Xu X, et al. Discovery of novel glutaminase 1 allosteric inhibitor with 4-piperidinamine linker and aromatic heterocycles. Eur J Med Chem. 2022 Jun 5;236:114337.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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