Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Axl-IN-6

Axl-IN-6 (compound 14) is an orally active and potent AXL inhibitor. Axl-IN-6 is well tolerated and significantly inhibits the tumor growth in MV-4-11 subcutaneous xenograft model[1].

Product Specifications

CAS Number

2642224-22-2

UNSPSC

12352005

Target

TAM Receptor

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/axl-in-6.html

Solubility

10 mM in DMSO

Smiles

CC(OC1=CC=C(C=C1)C2=CC=CC3=CN=C(N=C32)NC4=CC5=C(CC[C@@H](CC5)N6CCCC6)C=C4)C

Molecular Formula

C32H36N4O

Molecular Weight

492.65

References & Citations

[1]Zhang LL, et al. Discovery a series of quinazolin derivatives as potent AXL inhibitors. Eur J Med Chem. 2022 Apr 6;237:114316.[published online ahead of print, 2022 Apr 6]. Eur J Med Chem. 2022;237:114316.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Axl

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Mycophenolic Acid-d3 Acyl-Beta-D-glucuronide
TRC-M831527-5MG 5 mg

Mycophenolic Acid-d3 Acyl-Beta-D-glucuronide

Sign In for Pricing
View Details
AMDHD1 Mouse Monoclonal Antibody [Clone ID: OTI5B5]
CF809949 100 µg

AMDHD1 Mouse Monoclonal Antibody [Clone ID: OTI5B5]

Sign In for Pricing
View Details
Nuclear Blue™ DCS2 *Equivalent to SYTOX™ Blue Dead Cell Stain*
17546-AAT 0.5 mL

Nuclear Blue™ DCS2 *Equivalent to SYTOX™ Blue Dead Cell Stain*

Sign In for Pricing
View Details
D-Glucose-13C6
TRC-G595002-25MG 25 mg

D-Glucose-13C6

Sign In for Pricing
View Details
Smim6 Mouse Gene Knockout Kit (CRISPR)
KN516329 1 Kit

Smim6 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
RNF41 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2C1]
TA811158BM 100 µL

RNF41 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2C1]

Sign In for Pricing
View Details